Epidemiological Transition in Health and Longevity
“Epidemiologic transition”
Chronic and degenerative diseases are becoming the leading causes of death, overtaking infectious and acute diseases.
Degenerative disease
Progressive condition
• Worsening of symptoms over time
• Increasing cost of constant care
• Enormous societal burden
• Enormous overall economic cost
Current treatments
• Only control of symptoms or halt disease progression (in the best case)
• No reversal of occurred physiological and pathological damage
• No cure of degenerative diseases
Influencing Factors on Health and Longevity
Health and longevity are determined by an interplay of
1. Genetics
2. Environment
3. Lifestyle
• Impacting the body at molecular and cellular level
• Resulting in physical and physiological changes
• Accumulating damage
• Compromising quality control systems
• Causing functional capabilities to decline progressively
Characteristics and Indicators of Disease and Aging
1. Genetics
• Cell activation and inflammation
• Mitochondrial dysfunction
• Impaired adaptive stress response signaling
2. Environment
• Impaired molecular waste disposal
• Oxidative damage
• Dysregulated homeostasis
3. Lifestyle
• Stem cell exhaustion
• Impaired DNA repair
• Abnormal neuronal network activity
Activation of Stem Cells
Influencing Health and Longevity
Goal
• Providing a unique and non-invasive solution to improve chronic and degenerative conditions in an aging population
• With a solution that is safe and that is based on nature and natural science
Solution
• QFT-Activation of beneficial properties
• Stimulating the natural communication of stem cells
• Non-invasive
Approach
• Activating stem cells and initiating self-healing of the body
• Targeting mechanisms underlying disease and aging
• Promoting repair response at the molecular, cellular and tissue level
• Promoting individual immune response
• Showing restorative potential by creating a more youthful activation pattern
Effect of Stimulated Properties on Stem Cells
Promoting Repair and Immune Response
Extract and stimulate beneficial properties
• Activate and influence adult stem cells
• Stem cells initiate a calibration process and synchronize
• Enable adult stem cells to act similarly to embryonic stem cells
Multiple, synergistic levels of influence on the body:
Genetics, Environment (socioeconomics, environmental exposures), and
Lifestyle (dietary habits, microbiome, metabolism, physical activity)
• The body initiates self-healing according to personal / individual situation
• Promoting individual repair response
• Promoting individual immune response
Promoting individual repair response
The body decides itself what it reactivates / regenerates and promotes the respective repair response of:
1. Altered molecules
2. Diseased, dysfunctional or injured cells or
3. Tissue
Promoting individual immune response
The body decides itself what immune response it activates
• Promote repair response in the gut and restore gut homeostasis
• Improve the immune system interacting with the gut microbiome and metabolism (accelerated cell renewal)
• Improve the response to metabolic disorders, chronic inflammation, infection, and tolerance to food and antigens
Influence of Activated Stem Cells on Health and Longevity
Repair Response on Molecules, Cells, and Tissue
1. Promoting the repair of molecular alterations
• Extend DNA telomeres to rejuvenate different types of cells
• Repair DNA damage to prevent cancer
• Restore proteostatic balance in organs / cells for improved rejuvenation
• Reset epigenetic signature of a cell (to original state) to stimulate damage repair in its microenvironment
2. Promoting the repair of cellular dysfunction
• Stimulate functional divisions of existing stem cells to regenerate tissue
• Reduce abnormally activated growth signals to improve health-span and life-span
• Remove persistent pro-inflammatory cells to improve functioning of individual tissue and to extend health-span
• Restore mitochondrial energy function in aged tissue to reverse declining tissue function
3. Promoting the repair of tissue degeneration
• Reduce extracellular aggregates (like amyloids) in organs to retain normal function (e.g., brain and Alzheimer's)
• Reactivate, repair, and preserve the function of exhausted tissue to treat disease
• Renew stiffened ECM components (and respective inflammatory molecules) to regain proper functioning of nearby cells
• Reduce chronic inflammation by improving the immune system with accelerated cell renewal to reduce age-related damage and to prevent the development of major diseases
• Restore dysfunctional tissue (caused by changed endocrine signaling) to improve tissue functioning and to improve entire body functioning